Overview: Steve Elfrink is a pioneer in the field of psychedelic medicine and integrative healing, with over 40 years of experience. As the founder of OmTerra, he has dedicated his life to developing safe, trauma-informed approaches to psychedelic therapy. In his work, Steve combines personal insights with rigorous clinical research to help individuals navigate challenging psychedelic experiences and integrate profound healing. In this article, he shares his journey, professional expertise, and innovative methods for supporting recovery and transformation in those affected by trauma.
Psychedelic therapy offers powerful healing potential, but it can also sometimes stir up deep, unresolved emotional trauma. This is where the concept of Psychedelic Iatrogenic Structural Dissociation, or PISD, comes in. In simple terms, PISD refers to situations in which a psychedelic experience inadvertently reactivates hidden, dissociated parts of the self—often linked to early trauma—in a way that can feel destabilizing.
In PISD, a psychedelic experience can sometimes cause a sudden reactivation of the EP, overwhelming the ANP and causing feelings of confusion, anxiety, or being “split apart.”
Psychedelics are known for their ability to shift our perceptions and open us up to deep emotional experiences. For many, this can lead to profound healing. However, for some individuals—especially those with unresolved early trauma—these substances may:
Understanding PISD is crucial for both therapists and patients. It highlights the need for:
PISD is a concept still being explored by researchers and clinicians, with groundbreaking work published in respected journals like Frontiers in Psychology. By increasing awareness of how dissociation and trauma interact during psychedelic experiences, we can work towards safer and more effective therapeutic practices.
Whether you are a therapist seeking to support your clients or a patient considering psychedelic therapy, understanding PISD can empower you to approach these transformative experiences with care and informed guidance.
Remember, the goal of psychedelic therapy is healing. With proper screening, preparation, and integration, even challenging experiences can be transformed into opportunities for deep personal growth.
Reference
Elfrink, S., & Bergin, L. (2025). Psychedelic iatrogenic structural dissociation: an exploratory hypothesis on dissociative risks in psychedelic use. Frontiers in Psychology, 16. https://doi.org/10.3389/fpsyg.2025.1528253
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